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Tag Archives: Therapy

New Insights Into Protein Reveal Potential Therapy for Breast Cancer

Northwestern Medicine scientists have discovered a new function for a protein called SET1B in the cytoplasm of cells, and demonstrated that targeting its role in regulating cellular metabolism may be able to treat triple-negative breast cancer. The findings were published in the journal Genes and Development. “This is a major discovery,” said principal investigator Ali Shilatifard, PhD, the Robert Francis Furchgott Professor and chair ...

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Molecular profiling of melanoma tumours explains differences in survival after T cell therapy

Using the body’s own immune system to combat tumours, an approach known as immunotherapy, has brought a major breakthrough in cancer care. Whereas we previously had no treatments able to increase survival for certain cancer diagnoses, it is now possible to treat advanced melanoma, for example. One such immunotherapy method currently under clinical trial on patients with advanced melanoma is ...

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Clinical trial suggests new cell therapy for relapsed leukemia patients

This study gives hope to the idea that there may be another similar, very potent treatment. Mackall, professor of pediatrics and of internal medicine, is the senior author of the study, which was published online Nov. 20 in Nature Medicine. Terry Fry, MD, a pediatric hematologist and oncologist at the National Cancer Institute, is the lead author and led the conduct of the ...

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Autism Looms Larger on TV, But Industry Therapy Coverage Falls Short (OPINION)

“So, autism. That’s like the Rain Main savant thing, right?” Thanks to television shows such as “Parenthood,” “Atypical,” “The A Word” and “The Good Doctor,” conversations about autism are less likely to start with this type of under-informed exchange. The wider public is finally gaining more nuanced insight into the condition that impacts 1 out of 68 children in the ...

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Boy is given new skin thanks to gene therapy

A medical team at the Ruhr-Universität Bochum’s burn unit and the Center for Regenerative Medicine at the University of Modena (Italy) were the first ever to successfully treat a child suffering from extensive skin damage using transplants derived from genetically modified stem cells. The boy is a so-called butterfly child: he suffers from epidermolysis bullosa, a genetic skin disease that ...

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Fighting cancer with cancer: 3-D cultured cells could drive precision therapy

ANN ARBOR—Honeycomb-like arrays of tiny, lab-grown cancers could one day help doctors zero in on individualized treatments for ovarian cancer, an unpredictable disease that kills more than 14,000 women each year in the United States alone. A team of researchers has devised a process that can grow hundreds of cultured cell masses, called spheroids, from just a few tumor cells ...

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